Diagnostic yield of transbronchial lung cryobiopsy in interstitial lung diseases

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Diagnostic yield of transbronchial lung cryobiopsy in interstitial lung diseases.

Surgical lung biopsy (SLB) is still considered the gold standard procedure to obtain histology in interstitial lung diseases (ILD), the final diagnosis being decided on the basis of multidisciplinary assessment. The availability of a histological pattern may be very important in reaching diagnosis, predicting outcome and responding to treatment. There has been an increasing interest on transbro...

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Diagnostic yield of transbronchial cryobiopsy in non-neoplastic lung disease

Due to the small amount of alveolar tissue in transbronchial biopsy (TBB) by forceps, the diagnosis of diffuse, parenchymal lung diseases (DPLD) is inherently problematic, with an overall low yield. The use of cryotechnique in bronchoscopy, including TBB by cryoprobe, has revealed new opportunities in the endoscopical diagnosis of malignant and non-malignant lung diseases. To evaluate TBB by cr...

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Diagnostic yield of transbronchial cryobiopsy in interstitial lung disease: a randomized trial.

BACKGROUND AND OBJECTIVE Transbronchial lung biopsy (TBLB) is required for evaluation in selected patients with interstitial lung disease (ILD). The diagnostic yield of histopathologic assessment is variable and is influenced by factors such as the size of samples and the presence of crush artefacts left by conventional biopsy forceps. We compared the diagnostic yield and safety of TBLB with cr...

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Transbronchial Lung Cryobiopsy in the Diagnosis of Fibrotic Interstitial Lung Diseases

BACKGROUND Histology is a key element for the multidisciplinary diagnosis of fibrotic diffuse parenchymal lung diseases (f-DPLD) when the clinical-radiological picture is nondiagnostic. Transbronchial lung cryobiopsy (TBLC) have been shown to be useful for obtaining large and well-preserved biopsies of lung parenchyma, but experience with TBLC in f-DPLD is limited. OBJECTIVES To evaluate safe...

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Usefulness of Transbronchial Cryobiopsy in Interstitial Lung Disease

Interstitial lung disease (ILD) is a term that describes a group of more than 200 lung disorders that show varying degrees of infl ammation and fi brosis of the pulmonary interstitium. The etiology and pathophysiology of many of these disorders still remains poorly understood and is the topic of ongoing research and debate. The diagnostic approach to ILD can be complex and often requires a mult...

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ژورنال

عنوان ژورنال: Revista Portuguesa de Pneumologia (English Edition)

سال: 2017

ISSN: 2173-5115

DOI: 10.1016/j.rppnen.2017.07.002